| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50368778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31096 (CHEMBL640452) |
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| Ki | 1410000±n/a nM |
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| Citation |  Bussolari, JC; Ramesh, K; Stoeckler, JD; Chen, SF; Panzica, RP Synthesis and biological evaluation of N4-substituted imidazo- and v-triazolo[4,5-d]pyridazine nucleosides. J Med Chem36:4113-20 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA1 | ADA_HUMAN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40759.44 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human recombinant ADA was expressed and purified from an ADA-deficient bacterial strain. |
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| Residue: | 363 |
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| Sequence: | MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
QNL
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| BDBM50368778 |
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| n/a |
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| Name | BDBM50368778 |
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| Synonyms: | CHEMBL610668 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12N6O4 |
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| Mol. Mass. | 268.2294 |
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| SMILES | Nc1nncc2n(nnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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