| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
|---|
| Ligand | BDBM50403547 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_98922 (CHEMBL708731) |
|---|
| Ki | 0.120000±n/a nM |
|---|
| Citation |  McPherson, DW; DeHaven-Hudkins, DL; Callahan, AP; Knapp, FF Synthesis and biodistribution of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate. A new ligand for the potential imaging of muscarinic receptors by single photon emission computed tomography. J Med Chem36:848-54 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M3 |
|---|
| Name: | Muscarinic acetylcholine receptor M3 |
|---|
| Synonyms: | ACM3_RAT | Cholinergic, muscarinic M3 | Chrm-3 | Chrm3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66086.66 |
|---|
| Organism: | RAT |
|---|
| Description: | Cholinergic, muscarinic M3 CHRM3 RAT::P08483 |
|---|
| Residue: | 589 |
|---|
| Sequence: | MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLG
GHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS
MNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRT
TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFY
MPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVK
RSSRRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSET
RAIYSIVLKLPGHSSILNSTKLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQ
KDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRM
SLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNP
VCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
|
|
|
|---|
| BDBM50403547 |
|---|
| n/a |
|---|
| Name | BDBM50403547 |
|---|
| Synonyms: | ATROPEN | ATROPINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H23NO3 |
|---|
| Mol. Mass. | 289.3694 |
|---|
| SMILES | CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c1ccccc1 |r,THB:9:7:1:3.4| |
|---|
| Structure | 
|
|---|
Search and Browse
