Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Muscarinic acetylcholine receptor M2 | ||
Ligand | BDBM50456344 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_98750 (CHEMBL704479) | ||
Ki | 1.1±n/a nM | ||
Citation | McPherson, DW; DeHaven-Hudkins, DL; Callahan, AP; Knapp, FF Synthesis and biodistribution of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate. A new ligand for the potential imaging of muscarinic receptors by single photon emission computed tomography. J Med Chem36:848-54 (1993) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Muscarinic acetylcholine receptor M2 | |||
Name: | Muscarinic acetylcholine receptor M2 | ||
Synonyms: | ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 51555.53 | ||
Organism: | RAT | ||
Description: | P10980 | ||
Residue: | 466 | ||
Sequence: |
| ||
BDBM50456344 | |||
n/a | |||
Name | BDBM50456344 | ||
Synonyms: | CHEMBL2112942 | ||
Type | Small organic molecule | ||
Emp. Form. | C18H22INO3 | ||
Mol. Mass. | 427.2767 | ||
SMILES | OC(CC=CI)(C(=O)OC1CN2CCC1CC2)c1ccccc1 |(8.21,-10.55,;8.2,-9.01,;9.52,-9.78,;11.01,-9.37,;12.1,-10.45,;12.09,-12,;8.2,-7.46,;6.88,-6.69,;9.55,-6.69,;10.32,-5.34,;10.34,-3.8,;11.68,-3.03,;13,-3.83,;12.99,-5.35,;11.65,-6.11,;11,-5.18,;10.91,-4.29,;6.85,-9.78,;5.53,-8.97,;4.19,-9.75,;4.18,-11.27,;5.53,-12.06,;6.85,-11.3,)| | ||
Structure |