| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50003521 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_164922 (CHEMBL770633) |
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| IC50 | 1780±n/a nM |
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| Citation |  Lamouri, A; Heymans, F; Tavet, F; Dive, G; Batt, JP; Blavet, N; Braquet, P; Godfroid, JJ Design and modeling of new platelet-activating factor antagonists. 1. Synthesis and biological activity of 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-[[(substituted carbonyl and carbamoyl)oxy]methyl]piperazines. J Med Chem36:990-1000 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50003521 |
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| n/a |
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| Name | BDBM50003521 |
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| Synonyms: | CHEMBL6244 | [4-(3,4,5-Trimethoxy-benzoyl)-piperazin-1-yl]-(3,4,5-trimethoxy-phenyl)-methanone | [4-(3,4,5-Trimethoxy-benzoyl)-piperazin-1-yl]-(3,4,5-trimethoxy-phenyl)-methanone; hydrate |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N2O8 |
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| Mol. Mass. | 474.5036 |
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| SMILES | COc1cc(cc(OC)c1OC)C(=O)N1CCN(CC1)C(=O)c1cc(OC)c(OC)c(OC)c1 |
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| Structure | 
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