| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50046995 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_164922 (CHEMBL770633) |
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| IC50 | 1250±n/a nM |
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| Citation |  Lamouri, A; Heymans, F; Tavet, F; Dive, G; Batt, JP; Blavet, N; Braquet, P; Godfroid, JJ Design and modeling of new platelet-activating factor antagonists. 1. Synthesis and biological activity of 1,4-bis(3',4',5'-trimethoxybenzoyl)-2-[[(substituted carbonyl and carbamoyl)oxy]methyl]piperazines. J Med Chem36:990-1000 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Protein |
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| Mol. Mass.: | 39005.63 |
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| Organism: | Cavia porcellus |
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| Description: | n/a |
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| Residue: | 342 |
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| Sequence: | MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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| BDBM50046995 |
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| n/a |
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| Name | BDBM50046995 |
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| Synonyms: | CHEMBL6319 | Dibutyl-carbamic acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C34H49N3O10 |
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| Mol. Mass. | 659.767 |
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| SMILES | CCCCN(CCCC)C(=O)OCC1CN(CCN1C(=O)c1cc(OC)c(OC)c(OC)c1)C(=O)c1cc(OC)c(OC)c(OC)c1 |
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| Structure | 
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