| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] A |
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| Ligand | BDBM15581 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99933 (CHEMBL710497) |
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| IC50 | 1900±n/a nM |
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| Citation |  Mazouz, F; Gueddari, S; Burstein, C; Mansuy, D; Milcent, R 5-[4-(benzyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one derivatives and related analogues: new reversible, highly potent, and selective monamine oxidase type B inhibitors. J Med Chem36:1157-67 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] A |
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| Name: | Amine oxidase [flavin-containing] A |
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| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 59515.21 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 526 |
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| Sequence: | MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKL
SSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADR
QAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKD
VPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
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| BDBM15581 |
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| n/a |
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| Name | BDBM15581 |
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| Synonyms: | CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine | US8633208, Clorgyline | US9603833, Clorgyline | [3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15Cl2NO |
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| Mol. Mass. | 272.17 |
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| SMILES | CN(CCCOc1ccc(Cl)cc1Cl)CC#C |
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| Structure | 
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