| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-K receptor |
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| Ligand | BDBM50030155 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143201 (CHEMBL747339) |
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| IC50 | >10000±n/a nM |
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| Citation |  Josien, H; Lavielle, S; Brunissen, A; Saffroy, M; Torrens, Y; Beaujouan, JC; Glowinski, J; Chassaing, G Design and synthesis of side-chain conformationally restricted phenylalanines and their use for structure-activity studies on tachykinin NK-1 receptor. J Med Chem37:1586-601 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-K receptor |
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| Name: | Neuromedin-K receptor |
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| Synonyms: | NK3R_RAT | Neurokinin 3 receptor | Tac3r | Tacr3 |
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| Type: | n/a |
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| Mol. Mass.: | 51128.60 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_10983 |
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| Residue: | 452 |
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| Sequence: | MASVPRGENWTDGTVEVGTHTGNLSSALGVTEWLALQAGNFSSALGLPATTQAPSQVRAN
LTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDAS
VAAFNTLINFIYGLHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKP
RLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVII
LVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWL
PYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRW
CPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLFDPNDGDPTKSSRKKRAVPRD
PSANGCSHRGSKSASTTSSFISSPYTSVDEYS
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| BDBM50030155 |
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| n/a |
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| Name | BDBM50030155 |
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| Synonyms: | Arg-Pro-Lys-Pro-Gln-Gln-deltaZPhe-Phe-Gly-Leu-Met | CHEMBL264341 | CHEMBL265573 |
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| Type | Small organic molecule |
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| Emp. Form. | C63H96N18O13S |
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| Mol. Mass. | 1345.614 |
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| SMILES | CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(N)=N)=Cc1ccccc1)C(N)=O |w:85.88| |
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| Structure | 
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