| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50036873 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2107 (CHEMBL617142) |
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| IC50 | 3000±n/a nM |
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| Citation |  Podona, T; Guardiola-Lemaître, B; Caignard, DH; Adam, G; Pfeiffer, B; Renard, P; Guillaumet, G 3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies. J Med Chem37:1779-93 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT2A | 5HT2A_BOVIN | 5HTR2A | HTR2A | Serotonin 2a (5-HT2a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52578.24 |
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| Organism: | BOVINE |
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| Description: | 5-HT2A HTR2A BOVINE::Q75Z89 |
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| Residue: | 470 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLHADTRLYSTDFNSGEGNTSNAFNWTVDSENRTNLSCEGC
LSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSTLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADENFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRTKLASFSFLPQSSLSSEKLFQRSIH
REPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNRDVIEAL
LNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKS
SQLQMGPKKNSKKDDKTTDNDCTMVALGKEHPEDAPADSSNTVNEKVSCV
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| BDBM50036873 |
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| n/a |
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| Name | BDBM50036873 |
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| Synonyms: | 8-{5-[(5-Methoxy-chroman-3-yl)-propyl-amino]-pentyl}-8-aza-spiro[4.5]decane-7,9-dione; compound with oxalic acid | CHEMBL417550 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H40N2O4 |
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| Mol. Mass. | 456.6175 |
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| SMILES | CCCN(CCCCCN1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1 |
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| Structure | 
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