| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50038706 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200981 (CHEMBL801234) |
|---|
| Ki | 0.61±n/a nM |
|---|
| Citation |  Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Novel (4-phenylpiperidinyl)- and (4-phenylpiperazinyl)alkyl-spaced esters of 1-phenylcyclopentanecarboxylic acids as potent sigma-selective compounds. J Med Chem37:1964-70 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50038706 |
|---|
| n/a |
|---|
| Name | BDBM50038706 |
|---|
| Synonyms: | 1-Phenyl-cyclopentanecarboxylic acid 5-(4-phenyl-piperidin-1-yl)-pentyl ester; hydrochloride | CHEMBL542380 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H37NO2 |
|---|
| Mol. Mass. | 419.5989 |
|---|
| SMILES | O=C(OCCCCCN1CCC(CC1)c1ccccc1)C1(CCCC1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
