Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPlatelet activating factor receptor
LigandBDBM50038752
Substrate/Competitorn/a
Meas. Tech.ChEMBL_151699
Ki 1.9±n/a nM
Citation Sheppard GSPireh DCarrera GMBures MGHeyman HRSteinman DHDavidsen SKPhillips JGGuinn DEMay PD 3-(2-(3-Pyridinyl)thiazolidin-4-oyl)indoles, a novel series of platelet activating factor antagonists. J Med Chem 37:2011-32 (1994) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50038752
n/a
NameBDBM50038752
Synonyms:CHEMBL64636 | [6-(4-Fluoro-phenoxy)-1H-indol-3-yl]-((R)-2-pyridin-3-yl-thiazolidin-4-yl)-methanone
TypeSmall organic molecule
Emp. Form.C23H18FN3O2S
Mol. Mass.419.471
SMILESFc1ccc(Oc2ccc3c(c[nH]c3c2)C(=O)[C@@H]2CSC(N2)c2cccnc2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: