| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
|---|
| Ligand | BDBM50036772 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_201742 (CHEMBL809876) |
|---|
| Ki | 1.9±n/a nM |
|---|
| Citation |  Gilligan, PJ; Kergaye, AA; Lewis, BM; McElroy, JF Piperidinyltetralin sigma ligands. J Med Chem37:364-70 (1994) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma non-opioid intracellular receptor 1 |
|---|
| Name: | Sigma non-opioid intracellular receptor 1 |
|---|
| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 25124.85 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q99720 |
|---|
| Residue: | 223 |
|---|
| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
|---|
| BDBM50036772 |
|---|
| n/a |
|---|
| Name | BDBM50036772 |
|---|
| Synonyms: | 1'-(4-nitrobenzyl)spiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-one; hydrochloride | CHEMBL544123 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H22N2O3 |
|---|
| Mol. Mass. | 350.411 |
|---|
| SMILES | [O-][N+](=O)c1ccc(CN2CCC3(CC2)CCc2ccccc2C3=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
