| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
|---|
| Ligand | BDBM50035096 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2592 (CHEMBL617460) |
|---|
| IC50 | 83±n/a nM |
|---|
| Citation |  Perregaard, J; Moltzen, EK; Meier, E; Sánchez, C Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles. J Med Chem38:1998-2008 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2A |
|---|
| Name: | 5-hydroxytryptamine receptor 2A |
|---|
| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52852.05 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat cortex membranes 5-HT2A receptors. |
|---|
| Residue: | 471 |
|---|
| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
|
|
|
|---|
| BDBM50035096 |
|---|
| n/a |
|---|
| Name | BDBM50035096 |
|---|
| Synonyms: | 3-{4-[4-(2-Methoxy-phenyl)-piperidin-1-yl]-butyl}-1H-indole | CHEMBL61747 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H30N2O |
|---|
| Mol. Mass. | 362.5078 |
|---|
| SMILES | COc1ccccc1C1CCN(CCCCc2c[nH]c3ccccc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
