| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50035102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_202043 (CHEMBL809516) |
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| IC50 | 16±n/a nM |
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| Citation |  Perregaard, J; Moltzen, EK; Meier, E; Sánchez, C Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles. J Med Chem38:1998-2008 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50035102 |
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| n/a |
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| Name | BDBM50035102 |
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| Synonyms: | 1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-piperidin-1-yl]-butyl}-1H-indole | CHEMBL61539 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H30F2N2 |
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| Mol. Mass. | 444.5587 |
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| SMILES | Fc1ccc(cc1)C1CCN(CCCCc2cn(-c3ccc(F)cc3)c3ccccc23)CC1 |
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| Structure | 
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