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TargetBeta-3 adrenergic receptor
LigandBDBM50029051
Substrate/Competitorn/a
Meas. Tech.ChEMBL_39073 (CHEMBL651144)
EC50 1580±n/a nM
Citation Ruffolo, RR; Bondinell, W; Hieble, JP Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications. J Med Chem38:3681-716 (1995) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-3 adrenergic receptor
Name:Beta-3 adrenergic receptor
Synonyms:ADRB3_RAT | Adrb3 | Adrb3r | Adrenergic receptor beta | Beta-3 adrenergic receptor
Type:PROTEIN
Mol. Mass.:43161.83
Organism:Rattus norvegicus
Description:ChEMBL_1509452
Residue:400
Sequence:
MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIA
RTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTA
SIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGAD
AEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELG
RFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSL
CWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSY
GGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
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  Blast E-value cutoff:
BDBM50029051
n/a
NameBDBM50029051
Synonyms:(-)-arterenol | (-)-noradrenaline | (-)-norepinephrine | (R)-(-)-norepinephrine | (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol | (R)-noradrenaline | (R)-norepinephrine | 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | CHEMBL1437 | NOREPINEPHRINE
TypeSmall organic molecule
Emp. Form.C8H11NO3
Mol. Mass.169.1778
SMILESNC[C@H](O)c1ccc(O)c(O)c1 |r|
Structure
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