| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50048236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_59154 (CHEMBL671035) |
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| Ki | 176±n/a nM |
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| Citation |  Thurkauf, A; Yuan, J; Chen, X; Wasley, JW; Meade, R; Woodruff, KH; Huston, K; Ross, PC 1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding. J Med Chem38:4950-2 (1996) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DRD2 | DRD2_CHLAE | Dopamine D2 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50619.11 |
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| Organism: | Cercopithecus aethiops |
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| Description: | ChEMBL_59156 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSKIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRSHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKNHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50048236 |
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| n/a |
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| Name | BDBM50048236 |
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| Synonyms: | 1-[1-(1-Phenyl-1H-pyrrol-3-ylmethyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one | CHEMBL146557 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N4O |
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| Mol. Mass. | 372.4629 |
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| SMILES | O=c1[nH]c2ccccc2n1C1CCN(Cc2ccn(c2)-c2ccccc2)CC1 |
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| Structure | 
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