| Reaction Details |
|---|
 | Report a problem with these data |
| Target | E-selectin |
|---|
| Ligand | BDBM50422123 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_60882 (CHEMBL673529) |
|---|
| IC50 | 7000000±n/a nM |
|---|
| Citation |  Kogan, TP; Dupré, B; Keller, KM; Scott, IL; Bui, H; Market, RV; Beck, PJ; Voytus, JA; Revelle, BM; Scott, D Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids. J Med Chem38:4976-84 (1996) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| E-selectin |
|---|
| Name: | E-selectin |
|---|
| Synonyms: | ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66642.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1438995 |
|---|
| Residue: | 610 |
|---|
| Sequence: | MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
|
|
|
|---|
| BDBM50422123 |
|---|
| n/a |
|---|
| Name | BDBM50422123 |
|---|
| Synonyms: | CHEMBL2303953 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H21NO6 |
|---|
| Mol. Mass. | 371.3838 |
|---|
| SMILES | OC[C@H]1O[C@H](Oc2ccccc2-c2cccc(CC#N)c2)[C@@H](O)[C@H](O)[C@@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
