| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50033675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144300 (CHEMBL754345) |
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| IC50 | 1200±n/a nM |
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| Citation |  González-Muñiz, R; García-López, MT; Gómez-Monterrey, I; Herranz, R; Jimeno, ML; Suárez-Gea, ML; Johansen, NL; Madsen, K; Thøgersen, H; Suzdak, P Ketomethylene and (cyanomethylene)amino pseudopeptide analogues of the C-terminal hexapeptide of neurotensin. J Med Chem38:1015-21 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47070.64 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1466612 |
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| Residue: | 424 |
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| Sequence: | MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTD
IYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLA
MPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTL
MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQV
NTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY
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| BDBM50033675 |
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| n/a |
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| Name | BDBM50033675 |
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| Synonyms: | (S)-2-[(S)-5-({1-[2-(2-Amino-5-guanidino-pentanoylamino)-5-guanidino-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-2-benzyl-6-(4-hydroxy-phenyl)-4-oxo-hexanoylamino]-4-methyl-pentanoic acid | CHEMBL7674 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H63N11O8 |
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| Mol. Mass. | 850.0185 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C(CCCNC(N)=N)NC(=O)C(N)CCCNC(N)=N)Cc1ccccc1)C(O)=O |
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| Structure | 
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