| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50048871 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201746 (CHEMBL809880) |
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| Ki | 47±n/a nM |
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| Citation |  Berardi, F; Colabufo, NA; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives. J Med Chem39:176-82 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50048871 |
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| n/a |
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| Name | BDBM50048871 |
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| Synonyms: | 1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-4-(3,4,5,6-tetrahydro-pyridin-2-yl)-piperazine | CHEMBL50239 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H37N3O |
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| Mol. Mass. | 383.5701 |
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| SMILES | COc1cccc2C(CCCCN3CCN(CC3)C3=NCCCC3)CCCc12 |t:19| |
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| Structure | 
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