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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50036543 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
| IC50 | 160±n/a nM | ||
| Citation |  Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50036543 | |||
| n/a | |||
| Name | BDBM50036543 | ||
| Synonyms: | 4-Chloro-6-methyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulen-1-one | CHEMBL307994 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H20ClN3O | ||
| Mol. Mass. | 305.802 | ||
| SMILES | CC1N(CC=C(C)C)CCn2c3c1cc(Cl)cc3[nH]c2=O |(12.09,-10.6,;12.42,-9.08,;13.91,-8.75,;14.73,-10.09,;13.97,-11.44,;14.77,-12.77,;14.01,-14.11,;16.31,-12.75,;14.64,-7.12,;13.89,-5.79,;12.37,-5.54,;11.23,-6.59,;11.23,-8.13,;9.9,-8.9,;8.56,-8.13,;7.22,-8.92,;8.56,-6.59,;9.9,-5.82,;10.23,-4.3,;11.76,-4.16,;12.55,-2.83,)| | ||
| Structure | 
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