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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50050811 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
| IC50 | 480±n/a nM | ||
| Citation |  Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50050811 | |||
| n/a | |||
| Name | BDBM50050811 | ||
| Synonyms: | (6S,8R)-4-Chloro-6,8-dimethyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL308644 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H22ClN3S | ||
| Mol. Mass. | 335.895 | ||
| SMILES | C[C@@H]1Cn2c3c(cc(Cl)cc3[nH]c2=S)[C@H](C)N1CC=C(C)C |wU:14.16,1.0,(18.15,-5.16,;16.61,-5.18,;15.94,-3.8,;14.45,-3.46,;13.25,-4.42,;13.25,-5.96,;11.92,-6.73,;10.58,-5.96,;9.24,-6.75,;10.58,-4.42,;11.92,-3.65,;12.25,-2.13,;13.91,-2.01,;14.8,-.75,;14.45,-6.91,;14.1,-8.43,;15.94,-6.58,;16.9,-7.8,;16.32,-9.22,;17.27,-10.44,;18.81,-10.23,;16.71,-11.88,)| | ||
| Structure | 
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