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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50050812 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
| IC50 | 42±n/a nM | ||
| Citation |  Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50050812 | |||
| n/a | |||
| Name | BDBM50050812 | ||
| Synonyms: | (6R,8R)-6,8-Dimethyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL303015 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H23N3S | ||
| Mol. Mass. | 301.45 | ||
| SMILES | C[C@@H]1Cn2c3c(cccc3[nH]c2=S)[C@@H](C)N1CC=C(C)C |wU:1.0,wD:13.15,(15.41,-7.33,;13.87,-7.35,;13.19,-5.97,;11.7,-5.63,;10.51,-6.59,;10.51,-8.13,;9.18,-8.9,;7.84,-8.13,;7.84,-6.59,;9.18,-5.82,;9.5,-4.3,;11.16,-4.18,;12.06,-2.92,;11.7,-9.08,;11.36,-10.6,;13.19,-8.75,;14.15,-9.97,;13.58,-11.39,;14.54,-12.61,;13.96,-14.05,;16.06,-12.4,)| | ||
| Structure | 
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