Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Reverse transcriptase/RNaseH | ||
Ligand | BDBM50036498 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
IC50 | 2220±n/a nM | ||
Citation | Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Reverse transcriptase/RNaseH | |||
Name: | Reverse transcriptase/RNaseH | ||
Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
Type: | PROTEIN | ||
Mol. Mass.: | 65229.15 | ||
Organism: | Human immunodeficiency virus 1 | ||
Description: | ChEMBL_1473730 | ||
Residue: | 566 | ||
Sequence: |
| ||
BDBM50036498 | |||
n/a | |||
Name | BDBM50036498 | ||
Synonyms: | 8,9-Dimethyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL66043 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H23N3S | ||
Mol. Mass. | 301.45 | ||
SMILES | CC1C(C)n2c3c(CN1CC=C(C)C)cccc3[nH]c2=S |(15.42,-7.34,;13.88,-7.36,;13.22,-5.99,;14.17,-4.77,;11.72,-5.63,;10.51,-6.59,;10.51,-8.15,;11.72,-9.11,;13.22,-8.76,;14.17,-9.99,;13.6,-11.42,;14.55,-12.63,;13.97,-14.06,;16.09,-12.41,;9.18,-8.92,;7.85,-8.15,;7.85,-6.59,;9.18,-5.82,;9.51,-4.32,;11.17,-4.2,;12.08,-2.94,)| | ||
Structure |