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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50036496 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_195535 (CHEMBL800982) | ||
| IC50 | 23±n/a nM | ||
| Citation |  Silverman, BD; Platt, DE Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition. J Med Chem39:2129-40 (1996) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50036496 | |||
| n/a | |||
| Name | BDBM50036496 | ||
| Synonyms: | 4-Chloro-6-methyl-7-(3-methyl-but-2-enyl)-6,7,8,9-tetrahydro-2H-2,7,9a-triaza-benzo[cd]azulene-1-thione | CHEMBL304294 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H20ClN3S | ||
| Mol. Mass. | 321.868 | ||
| SMILES | CC1N(CC=C(C)C)CCn2c3c1cc(Cl)cc3[nH]c2=S |(12.06,-10.59,;12.39,-9.08,;13.88,-8.74,;14.7,-10.06,;13.94,-11.41,;14.74,-12.74,;16.27,-12.72,;13.98,-14.09,;14.6,-7.11,;13.86,-5.78,;12.35,-5.54,;11.2,-6.57,;11.2,-8.12,;9.88,-8.89,;8.54,-8.12,;7.2,-8.9,;8.54,-6.57,;9.88,-5.8,;10.2,-4.31,;11.73,-4.15,;12.52,-2.82,)| | ||
| Structure | 
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