| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate carboxypeptidase 2 |
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| Ligand | BDBM50048694 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_68365 (CHEMBL677065) |
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| Ki | 1.9±n/a nM |
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| Citation |  Jackson, PF; Cole, DC; Slusher, BS; Stetz, SL; Ross, LE; Donzanti, BA; Trainor, DA Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase. J Med Chem39:619-22 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate carboxypeptidase 2 |
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| Name: | Glutamate carboxypeptidase 2 |
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| Synonyms: | FOLH1_RAT | Folh1 | Glutamate carboxypeptidase II | Naalad1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 84547.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_68365 |
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| Residue: | 752 |
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| Sequence: | MWNAQQDSDSAEALGRRQRWFCAGTLVLAFTGTFIIGFLFGWFIKPSNDSTSSVSYPGMK
KAFLQELKAENIKKFLYNFTRTPHLAGTQHNFELAKQIHAQWKEFGLDLVELSDYDVLLS
YPNKTHPNYISIINEDGNEIFKTSLAELSPPGYENISDVVPPYSAFSPQGTPEGDLVYVN
YARTEDFFKLERVMKINCSGKIVIARYGQVFRGNKVKNAQLAGAKGIILYSDPADYFVPG
VKSYPDGWNLPGGGVQRGNVLNLNGAGDPLTPGYPANEYAYRHEFTEAVGLPSIPVHPIG
YDDAQKLLEHMGGSAPPDSSWKGGLKVPYNVGPGFAGNFSKQKVKLHIHSYNKVTRIYNV
IGTLKGAVEPDRYVILGGHRDAWVFGGIDPQSGAAVVHEIVRTFGTLKKKGWRPRRTILF
ASWDAEEFGLLGSTEWAEEHSRLLQERGVAYINADSSIEGNYTLRVDCTPLMHSLVYNLT
KELPSPDEGFEGKSLYDSWKEKSPSTEFIGMPRISKLGSGNDFEVFFQRLGIASGRARYT
KNWKNNKVSSYPLYHSVYETYELVEKFYDPTFKYHLTVAQVRGAMVFELANSIVLPFDCQ
SYAVALKKHAETIYNISMNHPQEMKAYMISFDSLFSAVNNFTDVASKFNQRLQDLDKSNP
ILLRILNDQLMYLERAFIDPLGLPGRPFYRHIIYAPSSHNKYAGESFPGIYDALFDINNK
VDTSKAWREVKRQISIAAFTVQAAAETLREVD
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| BDBM50048694 |
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| n/a |
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| Name | BDBM50048694 |
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| Synonyms: | 2-[(2-Carboxy-ethyl)-hydroxy-phosphinoylmethyl]-pentanedioic acid | CHEMBL156643 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15O8P |
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| Mol. Mass. | 282.1844 |
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| SMILES | OC(=O)CCC(CP(O)(=O)CCC(O)=O)C(O)=O |
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| Structure | 
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