| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM50054677 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31859 (CHEMBL643936) |
|---|
| Ki | 2750±n/a nM |
|---|
| Citation |  Jiang, JL; van Rhee, AM; Melman, N; Ji, XD; Jacobson, KA 6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem39:4667-75 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36197.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P0DMS8 |
|---|
| Residue: | 318 |
|---|
| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
|
|
|
|---|
| BDBM50054677 |
|---|
| n/a |
|---|
| Name | BDBM50054677 |
|---|
| Synonyms: | 2-Methyl-6-phenyl-4-phenylethynyl-pyridine-3,5-dicarboxylic acid 5-benzyl ester 3-ethyl ester | CHEMBL108797 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H25NO4 |
|---|
| Mol. Mass. | 475.5345 |
|---|
| SMILES | CCOC(=O)c1c(C)nc(-c2ccccc2)c(C(=O)OCc2ccccc2)c1C#Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
