| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Ligand | BDBM50032315 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_205199 (CHEMBL817369) |
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| IC50 | 50000±n/a nM |
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| Citation |  Takami, H; Koshimura, H; Kishibayashi, N; Ishii, A; Nonaka, H; Aoyama, S; Kase, H; Kumazawa, T Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors. J Med Chem39:5047-52 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Name: | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
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| Synonyms: | S5A1_RAT | Srd5a1 | Steroid 5-alpha-reductase | Steroid 5-alpha-reductase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 29788.29 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1441437 |
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| Residue: | 259 |
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| Sequence: | MVPLMELDELCLLDMLVYLEGFMAFVSIVGLRSVGSPYGRYSPQWPGIRVPARPAWFIQE
LPSMAWPLYEYIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLVTFVLA
FLFCTFNGYVQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGE
TGYKIPRGGLFEYVSAANYFGELVEWCGFALASWSLQGVVFALFTLSTLLTRAKQHHQWY
HEKFEDYPKSRKILIPFVL
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| BDBM50032315 |
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| n/a |
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| Name | BDBM50032315 |
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| Synonyms: | 4-{2-[(E)-3-(1-Benzyl-1H-indol-5-yl)-but-2-enoylamino]-phenoxy}-butyric acid | CHEMBL329483 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H28N2O4 |
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| Mol. Mass. | 468.5436 |
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| SMILES | C\C(=C/C(=O)Nc1ccccc1OCCCC(O)=O)c1ccc2n(Cc3ccccc3)ccc2c1 |
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| Structure | 
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