| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase A2 |
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| Ligand | BDBM50055413 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_156185 (CHEMBL760954) |
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| IC50 | 18000000±n/a nM |
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| Citation |  Teshirogi, I; Matsutani, S; Shirahase, K; Fujii, Y; Yoshida, T; Tanaka, K; Ohtani, M Synthesis and phospholipase A2 inhibitory activity of thielocin B3 derivatives. J Med Chem39:5183-91 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase A2 |
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| Name: | Phospholipase A2 |
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| Synonyms: | Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor |
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| Type: | Protein |
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| Mol. Mass.: | 16364.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P04054 |
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| Residue: | 148 |
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| Sequence: | MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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| BDBM50055413 |
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| n/a |
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| Name | BDBM50055413 |
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| Synonyms: | CHEMBL384002 | Thielocin B3 |
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| Type | Small organic molecule |
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| Emp. Form. | C62H66O20 |
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| Mol. Mass. | 1131.1754 |
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| SMILES | COc1c(C)c(OC(=O)c2c(C)c(C)c(OC(=O)c3c(C)cc(O)c(Cc4c(C)c(C(=O)Oc5c(C)c(C)c(C(=O)Oc6c(C)c(C)c(C(O)=O)c(OC)c6C)c(OC)c5C)c(O)c(C)c4O)c3O)c(C)c2OC)c(C)c(C)c1C(O)=O |
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| Structure | 
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