| Reaction Details |
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 | Report a problem with these data |
| Target | Thyrotropin-releasing hormone receptor |
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| Ligand | BDBM50050532 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_207855 (CHEMBL810063) |
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| Ki | 1500±n/a nM |
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| Citation |  Rutledge, LD; Perlman, JH; Gershengorn, MC; Marshall, GR; Moeller, KD Conformationally restricted TRH analogs: a probe for the pyroglutamate region. J Med Chem39:1571-4 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thyrotropin-releasing hormone receptor |
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| Name: | Thyrotropin-releasing hormone receptor |
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| Synonyms: | TRH-R | TRHR_MOUSE | Thyroliberin receptor | Trhr | thyrotropin-releasing hormone R1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44568.52 |
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| Organism: | MOUSE |
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| Description: | thyrotropin-releasing hormone R1 TRHR MOUSE::P21761 |
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| Residue: | 393 |
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| Sequence: | MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPT
NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCG
YKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIH
QNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKES
DRFSTELEDITVTDTYVSTTKVSFDDTCLASEN
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| BDBM50050532 |
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| n/a |
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| Name | BDBM50050532 |
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| Synonyms: | 1-[2-[2-oxo-(5S)-dihydro-2H-5-pyrrolylcarboxamido]-3-phenyl-(2S)-propanoyl]-(2S)-tetrahydro-1H-2-pyrrolecarboxamide | CHEMBL36631 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N4O4 |
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| Mol. Mass. | 372.4183 |
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| SMILES | NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1 |
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| Structure | 
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