| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, brain form |
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| Ligand | BDBM50057742 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_70987 (CHEMBL680565) |
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| Ki | 59700±n/a nM |
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| Citation |  Pastor, M; Cruciani, G; Clementi, S Smart region definition: a new way to improve the predictive ability and interpretability of three-dimensional quantitative structure-activity relationships. J Med Chem40:1455-64 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, brain form |
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| Name: | Glycogen phosphorylase, brain form |
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| Synonyms: | Brain glycogen phosphorylase | Glycogen phosphorylase, brain form | PYGB | PYGB_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96699.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_70998 |
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| Residue: | 843 |
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| Sequence: | MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTV
RDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDL
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA
DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVN
TMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV
DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFP
GDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKF
QNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ
ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFV
PRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPA
ADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE
ALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEA
YMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI
PRD
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| BDBM50057742 |
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| n/a |
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| Name | BDBM50057742 |
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| Synonyms: | 9,10,11-Trihydroxy-8-hydroxymethyl-7-oxa-1,4-diaza-spiro[5.5]undecane-2,5-dione | CHEMBL33030 | O=C1C2(C(C(O)C(C(O2)CO)O)O)NC(=O)CN1 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H14N2O7 |
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| Mol. Mass. | 262.2167 |
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| SMILES | OCC1OC2(NC(=O)CNC2=O)C(O)C(O)C1O |
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| Structure | 
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