Ki Summary

Reaction Details

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Target

Somatostatin receptor type 5

Ligand

BDBM50059089

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_200526 (CHEMBL806596)

IC50

4.9±n/a nM

Citation

Osapay, G; Prokai, L; Kim, HS; Medzihradszky, KF; Coy, DH; Liapakis, G; Reisine, T; Melacini, G; Zhu, Q; Wang, SH; Mattern, RH; Goodman, M Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies. J Med Chem40:2241-51 (1997) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Somatostatin receptor type 5

Name:

Somatostatin receptor type 5

Synonyms:

SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5)

Type:

Enzyme

Mol. Mass.:

39218.02

Organism:

Homo sapiens (Human)

Description:

P35346

Residue:

364

Sequence:

MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL

BDBM50059089

n/a

Name

BDBM50059089

Synonyms:

9-(4-Amino-butyl)-18-(2-amino-3-phenyl-propionylamino)-15-benzyl-6-(1-hydroxy-ethyl)-12-(1H-indol-3-ylmethyl)-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaaza-cyclononadecane-3-carboxylic acid (1-carbamoyl-2-hydroxy-propyl)-amide | CHEMBL436783

Type

Small organic molecule

Emp. Form.

C49H65N11O10S

Mol. Mass.

1000.173

SMILES

C[C@@H](O)[C@H](NC(=O)[C@@H]1CSC[C@@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(N)=O

Structure