| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50060063 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_48481 (CHEMBL662059) |
|---|
| Ki | 120000±n/a nM |
|---|
| Citation |  Stürzebecher, J; Prasa, D; Hauptmann, J; Vieweg, H; Wikström, P Synthesis and structure-activity relationships of potent thrombin inhibitors: piperazides of 3-amidinophenylalanine. J Med Chem40:3091-9 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54498.45 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1364435 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
|
|
|
|---|
| BDBM50060063 |
|---|
| n/a |
|---|
| Name | BDBM50060063 |
|---|
| Synonyms: | 3-[3-(4-Methanesulfonyl-piperazin-1-yl)-2-(4-methoxy-2,3,6-trimethyl-benzenesulfonylamino)-3-oxo-propyl]-benzamidine | CHEMBL105439 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H35N5O6S2 |
|---|
| Mol. Mass. | 565.705 |
|---|
| SMILES | COc1cc(C)c(c(C)c1C)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCN(CC1)S(C)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
