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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 4 | ||
| Ligand | BDBM50056399 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_3253 (CHEMBL619759) | ||
| IC50 | 30±n/a nM | ||
| Citation |  Yang, D; Soulier, JL; Sicsic, S; Mathé-Allainmat, M; Brémont, B; Croci, T; Cardamone, R; Aureggi, G; Langlois, M New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem40:608-21 (1997) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 4 | |||
| Name: | 5-hydroxytryptamine receptor 4 | ||
| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 43735.29 | ||
| Organism: | GUINEA PIG | ||
| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 | ||
| Residue: | 388 | ||
| Sequence: |
| ||
| BDBM50056399 | |||
| n/a | |||
| Name | BDBM50056399 | ||
| Synonyms: | 4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester | CHEMBL41769 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H19ClN2O3 | ||
| Mol. Mass. | 310.776 | ||
| SMILES | COc1cc(N)c(Cl)cc1C(=O)O[C@H]1CN2CCC1CC2 |wD:13.13,(5.68,-9.92,;5.68,-8.38,;4.35,-7.61,;3.01,-8.38,;1.68,-7.61,;.33,-8.38,;1.68,-6.07,;.35,-5.3,;3.01,-5.3,;4.35,-6.07,;5.68,-5.3,;5.67,-3.76,;7.01,-6.04,;8.34,-5.28,;9.67,-6.04,;11,-5.28,;11,-3.74,;9.67,-2.97,;8.33,-3.74,;9.08,-5.07,;10.18,-3.97,)| | ||
| Structure | 
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