| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50056392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3253 (CHEMBL619759) |
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| IC50 | 13±n/a nM |
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| Citation |  Yang, D; Soulier, JL; Sicsic, S; Mathé-Allainmat, M; Brémont, B; Croci, T; Cardamone, R; Aureggi, G; Langlois, M New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem40:608-21 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43735.29 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
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| BDBM50056392 |
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| n/a |
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| Name | BDBM50056392 |
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| Synonyms: | 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(3,5-dimethyl-piperidin-1-yl)-ethyl ester | CHEMBL155917 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25ClN2O3 |
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| Mol. Mass. | 340.845 |
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| SMILES | COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)CC(C)C1 |
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| Structure | 
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