Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 4 | ||
Ligand | BDBM50056399 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_3340 (CHEMBL619040) | ||
Ki | 488±n/a nM | ||
Citation | Yang, D; Soulier, JL; Sicsic, S; Mathé-Allainmat, M; Brémont, B; Croci, T; Cardamone, R; Aureggi, G; Langlois, M New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem40:608-21 (1997) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 4 | |||
Name: | 5-hydroxytryptamine receptor 4 | ||
Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 46117.31 | ||
Organism: | RAT | ||
Description: | 5-HT4 HTR4 RAT::Q62758 | ||
Residue: | 406 | ||
Sequence: |
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BDBM50056399 | |||
n/a | |||
Name | BDBM50056399 | ||
Synonyms: | 4-Amino-5-chloro-2-methoxy-benzoic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester | CHEMBL41769 | ||
Type | Small organic molecule | ||
Emp. Form. | C15H19ClN2O3 | ||
Mol. Mass. | 310.776 | ||
SMILES | COc1cc(N)c(Cl)cc1C(=O)O[C@H]1CN2CCC1CC2 |wD:13.13,(5.68,-9.92,;5.68,-8.38,;4.35,-7.61,;3.01,-8.38,;1.68,-7.61,;.33,-8.38,;1.68,-6.07,;.35,-5.3,;3.01,-5.3,;4.35,-6.07,;5.68,-5.3,;5.67,-3.76,;7.01,-6.04,;8.34,-5.28,;9.67,-6.04,;11,-5.28,;11,-3.74,;9.67,-2.97,;8.33,-3.74,;9.08,-5.07,;10.18,-3.97,)| | ||
Structure |