| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
|---|
| Ligand | BDBM50056398 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_3340 (CHEMBL619040) |
|---|
| Ki | 7.8±n/a nM |
|---|
| Citation |  Yang, D; Soulier, JL; Sicsic, S; Mathé-Allainmat, M; Brémont, B; Croci, T; Cardamone, R; Aureggi, G; Langlois, M New esters of 4-amino-5-chloro-2-methoxybenzoic acid as potent agonists and antagonists for 5-HT4 receptors. J Med Chem40:608-21 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 4 |
|---|
| Name: | 5-hydroxytryptamine receptor 4 |
|---|
| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 46117.31 |
|---|
| Organism: | RAT |
|---|
| Description: | 5-HT4 HTR4 RAT::Q62758 |
|---|
| Residue: | 406 |
|---|
| Sequence: | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSN
STFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
|
|
|
|---|
| BDBM50056398 |
|---|
| n/a |
|---|
| Name | BDBM50056398 |
|---|
| Synonyms: | 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(2-methyl-piperidin-1-yl)-ethyl ester | CHEMBL349809 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H23ClN2O3 |
|---|
| Mol. Mass. | 326.818 |
|---|
| SMILES | COc1cc(N)c(Cl)cc1C(=O)OCCN1CCCCC1C |
|---|
| Structure | 
|
|---|
Search and Browse
