| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50064614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139081 (CHEMBL745817) |
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| Ki | 25000±n/a nM |
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| Citation |  Pei, XF; Gupta, TH; Badio, B; Padgett, WL; Daly, JW 6beta-Acetoxynortropane: a potent muscarinic agonist with apparent selectivity toward M2-receptors. J Med Chem41:2047-55 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50064614 |
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| n/a |
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| Name | BDBM50064614 |
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| Synonyms: | 2-Methoxycarbonyl-8-methyl-8-azonia-bicyclo[3.2.1]oct-2-ene | 8-Methyl-8-aza-bicyclo[3.2.1]oct-2-ene-2-carboxylic acid methyl ester | CHEMBL412663 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15NO2 |
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| Mol. Mass. | 181.2316 |
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| SMILES | COC(=O)C1=CCC2CCC1N2C |t:4,THB:2:4:11:9.8| |
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| Structure | 
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