| Reaction Details |
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 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase |
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| Ligand | BDBM50068147 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72770 (CHEMBL681383) |
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| IC50 | 4000±n/a nM |
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| Citation |  Aronov, AM; Verlinde, CL; Hol, WG; Gelb, MH Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design. J Med Chem41:4790-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glyceraldehyde-3-phosphate dehydrogenase |
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| Name: | Glyceraldehyde-3-phosphate dehydrogenase |
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| Synonyms: | G3P_HUMAN | GAPD | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase liver |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36060.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1511315 |
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| Residue: | 335 |
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| Sequence: | MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTV
KAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVI
ISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHA
ITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANV
SVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAG
IALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE
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| BDBM50068147 |
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| n/a |
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| Name | BDBM50068147 |
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| Synonyms: | CHEMBL356360 | N-{4-Hydroxy-5-hydroxymethyl-2-[6-(2-methyl-benzylamino)-purin-9-yl]-tetrahydro-furan-3-yl}-3-methoxy-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28N6O5 |
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| Mol. Mass. | 504.5377 |
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| SMILES | COc1cccc(c1)C(=O)NC1C(O)C(CO)OC1n1cnc2c(NCc3ccccc3C)ncnc12 |
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| Structure | 
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