| Reaction Details |
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 | Report a problem with these data |
| Target | L-selectin |
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| Ligand | BDBM50422280 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_199990 (CHEMBL810875) |
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| IC50 | 750000±n/a nM |
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| Citation |  Kogan, TP; Dupré, B; Bui, H; McAbee, KL; Kassir, JM; Scott, IL; Hu, X; Vanderslice, P; Beck, PJ; Dixon, RA Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269). J Med Chem41:1099-111 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| L-selectin |
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| Name: | L-selectin |
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| Synonyms: | LNHR | LYAM1 | LYAM1_HUMAN | Leukocyte adhesion molecule-1 | SELL | Selectin |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42187.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_200000 |
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| Residue: | 372 |
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| Sequence: | MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN
YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN
NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC
NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT
CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK
TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK
GKKSKRSMNDPY
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| BDBM50422280 |
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| n/a |
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| Name | BDBM50422280 |
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| Synonyms: | CHEMBL2303893 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H44O14 |
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| Mol. Mass. | 748.769 |
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| SMILES | OC[C@H]1O[C@H](Oc2ccccc2-c2cccc(CCc3ccc(O[C@H]4O[C@H](CO)[C@@H](O)[C@@H](O)[C@@H]4O)c(c3)-c3cccc(CC(O)=O)c3)c2)[C@@H](O)[C@H](O)[C@@H]1O |r| |
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| Structure | 
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