| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM50118242 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_162354 (CHEMBL768362) |
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| EC50 | 1.9±n/a nM |
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| Citation |  Moro, S; Guo, D; Camaioni, E; Boyer, JL; Harden, TK; Jacobson, KA Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites. J Med Chem41:1456-66 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM50118242 |
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| n/a |
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| Name | BDBM50118242 |
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| Synonyms: | ((2R,3S,4R,5R)-5-(6-amino-2-(methylthio)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate | ((2S,3R,4S,5S)-5-(6-amino-2-(methylthio)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate | 2-MeS-ADP | 2-MeSADP | CHEMBL435402 | [({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N5O10P2S |
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| Mol. Mass. | 473.293 |
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| SMILES | CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 |r| |
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| Structure | 
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