Reaction Details |
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Target | Ornithine transcarbamylase, mitochondrial |
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Ligand | BDBM50079020 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_148265 (CHEMBL753865) |
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pH | 7±n/a |
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Ki | 265000±n/a nM |
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Comments | extracted |
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Citation | Flohr, A; Aemissegger, A; Hilvert, D alpha-Functionalized phosphonylphosphinates: synthesis and evaluation as transcarbamoylase inhibitors. J Med Chem42:2633-40 (1999) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Ornithine transcarbamylase, mitochondrial |
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Name: | Ornithine transcarbamylase, mitochondrial |
Synonyms: | OTC | OTC_HUMAN | Ornithine carbamoyltransferase |
Type: | PROTEIN |
Mol. Mass.: | 39943.22 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_148264 |
Residue: | 354 |
Sequence: | MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLS
ADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV
NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQ
EHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKEN
GTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTF
LHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
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BDBM50079020 |
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n/a |
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Name | BDBM50079020 |
Synonyms: | (Aminomethyl-hydroxy-phosphinoylmethyl)-phosphonic acid |
Type | Small organic molecule |
Emp. Form. | C2H8NO5P2 |
Mol. Mass. | 188.0367 |
SMILES | [NH3+]CP([O-])(=O)CP(O)([O-])=O |
Structure |
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