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TargetOrnithine transcarbamylase, mitochondrial
LigandBDBM50162816
Substrate/Competitorn/a
Meas. Tech.ChEMBL_148264 (CHEMBL753864)
pH8±n/a
Ki 9000000±n/a nM
Commentsextracted
Citation Flohr, AAemissegger, AHilvert, D alpha-Functionalized phosphonylphosphinates: synthesis and evaluation as transcarbamoylase inhibitors. J Med Chem42:2633-40 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Ornithine transcarbamylase, mitochondrial
Name:Ornithine transcarbamylase, mitochondrial
Synonyms:OTC | OTC_HUMAN | Ornithine carbamoyltransferase
Type:PROTEIN
Mol. Mass.:39943.22
Organism:Homo sapiens (Human)
Description:ChEMBL_148264
Residue:354
Sequence:
MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLS
ADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV
NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQ
EHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKEN
GTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTF
LHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
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  Blast E-value cutoff:
BDBM50162816
n/a
NameBDBM50162816
Synonyms:CHEMBL180570 | Medronic acid | Methylene diphsphonate | Phosphonomethyl-phosphonic acid | methylenediphosphonic acid
TypeSmall organic molecule
Emp. Form.CH6O6P2
Mol. Mass.176.0023
SMILESOP(O)(=O)CP(O)(O)=O
Structure
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