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TargetOrnithine transcarbamylase, mitochondrial
LigandBDBM50079020
Substrate/Competitorn/a
Meas. Tech.ChEMBL_148264 (CHEMBL753864)
pH8±n/a
Ki 800000±n/a nM
Commentsextracted
Citation Flohr, AAemissegger, AHilvert, D alpha-Functionalized phosphonylphosphinates: synthesis and evaluation as transcarbamoylase inhibitors. J Med Chem42:2633-40 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Ornithine transcarbamylase, mitochondrial
Name:Ornithine transcarbamylase, mitochondrial
Synonyms:OTC | OTC_HUMAN | Ornithine carbamoyltransferase
Type:PROTEIN
Mol. Mass.:39943.22
Organism:Homo sapiens (Human)
Description:ChEMBL_148264
Residue:354
Sequence:
MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLS
ADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGV
NESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQ
EHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKEN
GTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTF
LHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50079020
n/a
NameBDBM50079020
Synonyms:(Aminomethyl-hydroxy-phosphinoylmethyl)-phosphonic acid
TypeSmall organic molecule
Emp. Form.C2H8NO5P2
Mol. Mass.188.0367
SMILES[NH3+]CP([O-])(=O)CP(O)([O-])=O
Structure
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