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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 4 | ||
| Ligand | BDBM50083192 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_3345 (CHEMBL619045) | ||
| Ki | >1000±n/a nM | ||
| Citation |  López-Rodríguez, ML; Benhamú, B; Morcillo, MJ; Tejada, ID; Orensanz, L; Alfaro, MJ; Martín, MI Benzimidazole derivatives. 2. Synthesis and structure-activity relationships of new azabicyclic benzimidazole-4-carboxylic acid derivatives with affinity for serotoninergic 5-HT(3) receptors. J Med Chem42:5020-8 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| 5-hydroxytryptamine receptor 4 | |||
| Name: | 5-hydroxytryptamine receptor 4 | ||
| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46117.31 | ||
| Organism: | RAT | ||
| Description: | 5-HT4 HTR4 RAT::Q62758 | ||
| Residue: | 406 | ||
| Sequence: |
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| BDBM50083192 | |||
| n/a | |||
| Name | BDBM50083192 | ||
| Synonyms: | 1H-Benzoimidazole-4-carboxylic acid (1-aza-bicyclo[2.2.2]oct-3-yl)-amide | CHEMBL18274 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H18N4O | ||
| Mol. Mass. | 270.3296 | ||
| SMILES | O=C(NC1CN2CCC1CC2)c1cccc2nc[nH]c12 |THB:2:3:9.10:7.6,(4.09,-2.08,;4.08,-3.62,;5.41,-4.39,;6.75,-3.64,;7.8,-4.64,;7.25,-2.85,;8.5,-1.48,;7.53,-.47,;6.32,-1.82,;5.26,-1.62,;5.91,-2.57,;2.74,-4.39,;1.41,-3.61,;.07,-4.38,;.07,-5.91,;1.4,-6.7,;1.71,-8.22,;3.25,-8.38,;3.88,-6.97,;2.74,-5.93,)| | ||
| Structure | 
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