| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM50074268 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_28139 (CHEMBL644923) |
|---|
| IC50 | 13000±n/a nM |
|---|
| Citation |  Contreras, JM; Rival, YM; Chayer, S; Bourguignon, JJ; Wermuth, CG Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem42:730-41 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | 3.1.1.7 | ACES_TETCF | Acetylcholinesterase (AChE) | Acetylcholinesterase precursor | ache |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 65900.74 |
|---|
| Organism: | Tetronarce californica (Pacific electric ray) (Torpedo californica) |
|---|
| Description: | P04058 |
|---|
| Residue: | 586 |
|---|
| Sequence: | MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPP
VGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNI
WVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALH
GSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLF
RRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEW
NVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGF
SKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHN
VICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYT
AEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQ
MCVFWNQFLPKLLNATACDGELSSSGTSSSKGIIFYVLFSILYLIF
|
|
|
|---|
| BDBM50074268 |
|---|
| n/a |
|---|
| Name | BDBM50074268 |
|---|
| Synonyms: | CHEMBL1083055 | CHEMBL545585 | N-Benzyl-N-methyl-N'-(6-phenyl-pyridazin-3-yl)-propane-1,3-diamine; hydrochloride |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24N4 |
|---|
| Mol. Mass. | 332.4421 |
|---|
| SMILES | CN(CCCNc1ccc(nn1)-c1ccccc1)Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
