| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50088356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_88616 (CHEMBL701720) |
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| IC50 | 1080±n/a nM |
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| Citation |  Carlson, HA; Masukawa, KM; Rubins, K; Bushman, FD; Jorgensen, WL; Lins, RD; Briggs, JM; McCammon, JA Developing a dynamic pharmacophore model for HIV-1 integrase. J Med Chem43:2100-14 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50088356 |
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| n/a |
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| Name | BDBM50088356 |
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| Synonyms: | 1,3-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-4,5-dihydroxy-cyclohexanecarboxylic acid | CHEMBL431948 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24O12 |
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| Mol. Mass. | 516.4509 |
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| SMILES | OC1CC(CC(OC(=O)\C=C/c2ccc(O)c(O)c2)C1O)(OC(=O)\C=C/c1ccc(O)c(O)c1)C(O)=O |
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| Structure | 
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