| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 3 |
|---|
| Ligand | BDBM50084137 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106383 (CHEMBL717238) |
|---|
| Ki | >100000±n/a nM |
|---|
| Citation |  Bräuner-Osborne, H; Egebjerg, J; Nielsen, EO; Madsen, U; Krogsgaard-Larsen, P Ligands for glutamate receptors: design and therapeutic prospects. J Med Chem43:2609-45 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 3 |
|---|
| Name: | Metabotropic glutamate receptor 3 |
|---|
| Synonyms: | GPRC1C | GRM3 | GRM3_HUMAN | MGLUR3 | metabotropic glutamate 3 | metabotropic glutamate 3/1a | metabotropic glutamate 3/1c |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 98889.09 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | metabotropic glutamate 1c 0 HUMAN::Q14832 |
|---|
| Residue: | 879 |
|---|
| Sequence: | MKMLTRLQVLTLALFSKGFLLSLGDHNFLRREIKIEGDLVLGGLFPINEKGTGTEECGRI
NEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKV
DEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSD
KSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNIC
IATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAASRANASFTWVAS
DGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQ
CSLQNKRNHRRVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCD
AMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSY
LKVGHWAETLSLDVNSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYL
ADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIK
HNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALL
TKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLA
EKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCI
IWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLH
LNRFSVSGTGTTYSQSSASTYVPTVCNGREVLDSTTSSL
|
|
|
|---|
| BDBM50084137 |
|---|
| n/a |
|---|
| Name | BDBM50084137 |
|---|
| Synonyms: | 2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-phenylethynyl-pyridine | 2-Methyl-6-phenylethynyl-pyridine(MPEP) | 2-methyl-6-(2-phenylethynyl)pyridine | 2-methyl-6-(phenyl-ethynyl)pyridine | 2-methyl-6-(phenylethynyl)-pyridine | 6-methyl-2-(2-phenylethynyl)pyridine | CHEMBL1788108 | CHEMBL66654 | MPEP | US10618900, No. MPEP | [3H]-2-methyl-6-(phenylethynyl)-pyridine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H11N |
|---|
| Mol. Mass. | 193.2438 |
|---|
| SMILES | Cc1cccc(n1)C#Cc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
