| Reaction Details |
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 | Report a problem with these data |
| Target | E-selectin |
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| Ligand | BDBM50087287 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_199877 (CHEMBL803778) |
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| IC50 | 86000±n/a nM |
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| Citation |  Hiramatsu, Y; Tsukida, T; Nakai, Y; Inoue, Y; Kondo, H Study on selectin blocker. 8. Lead discovery of a non-sugar antagonist using a 3D-pharmacophore model. J Med Chem43:1476-83 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| E-selectin |
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| Name: | E-selectin |
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| Synonyms: | Elam-1 | LYAM2_MOUSE | Sele | Selectin E |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66749.86 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_199837 |
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| Residue: | 612 |
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| Sequence: | MNASRFLSALVFVLLAGESTAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLN
SNLKHSPSYYWIGIRKVNNVWIWVGTGKPLTEEAQNWAPGEPNNKQRNEDCVEIYIQRTK
DSGMWNDERCNKKKLALCYTASCTNASCSGHGECIETINSYTCKCHPGFLGPNCEQAVTC
KPQEHPDYGSLNCSHPFGPFSYNSSCSFGCKRGYLPSSMETTVRCTSSGEWSAPAPACHV
VECEALTHPAHGIRKCSSNPGSYPWNTTCTFDCVEGYRRVGAQNLQCTSSGIWDNETPSC
KAVTCDAIPQPQNGFVSCSHSTAGELAFKSSCNFTCEQSFTLQGPAQVECSAQGQWTPQI
PVCKAVQCEALSAPQQGNMKCLPSASGPFQNGSSCEFSCEEGFELKGSRRLQCGPRGEWD
SKKPTCSAVKCDDVPRPQNGVMECAHATTGEFTYKSSCAFQCNEGFSLHGSAQLECTSQG
KWTQEVPSCQVVQCPSLDVPGKMNMSCSGTAVFGTVCEFTCPDDWTLNGSAVLTCGATGR
WSGMPPTCEAPVSPTRPLVVALSAAGTSLLTSSSLLYLLMRYFRKKAKKFVPASSCQSLQ
SFENYHVPSYNV
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| BDBM50087287 |
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| n/a |
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| Name | BDBM50087287 |
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| Synonyms: | 4-(3-Carboxy-phenoxy)-3-(4-octadecanoylamino-benzoylamino)-benzoic acid | CHEMBL37284 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H50N2O7 |
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| Mol. Mass. | 658.8235 |
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| SMILES | CCCCCCCCCCCCCCCCCC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1Oc1cccc(c1)C(O)=O)C(O)=O |
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| Structure | 
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