| Reaction Details |
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 | Report a problem with these data |
| Target | Glycogen phosphorylase, brain form |
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| Ligand | BDBM50102880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_138353 (CHEMBL878565) |
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| Ki | 16500±n/a nM |
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| Citation |  Somsák, L; Kovács, L; Tóth, M; Osz, E; Szilágyi, L; Györgydeák, Z; Dinya, Z; Docsa, T; Tóth, B; Gergely, P Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco- and d-xylopyranosylidene-spiro-(thio)hydantoins and N-(d-glucopyranosyl) amides. J Med Chem44:2843-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glycogen phosphorylase, brain form |
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| Name: | Glycogen phosphorylase, brain form |
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| Synonyms: | Brain glycogen phosphorylase | Glycogen phosphorylase, brain form | PYGB | PYGB_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 96699.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_70998 |
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| Residue: | 843 |
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| Sequence: | MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTV
RDHLVGRWIRTQQHYYERDPKRIYYLSLEFYMGRTLQNTMVNLGLQNACDEAIYQLGLDL
EELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA
DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVN
TMRLWSAKAPNDFKLQDFNVGDYIEAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFV
VAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV
DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFP
GDVDRLRRMSVIEEGDCKRINMAHLCVIGSHAVNGVARIHSEIVKQSVFKDFYELEPEKF
QNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ
ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFV
PRTVMIGGKAAPGYHMAKLIIKLVTSIGDVVNHDPVVGDRLKVIFLENYRVSLAEKVIPA
ADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE
ALDRKGYNAREYYDHLPELKQAVDQISSGFFSPKEPDCFKDIVNMLMHHDRFKVFADYEA
YMQCQAQVDQLYRNPKEWTKKVIRNIACSGKFSSDRTITEYAREIWGVEPSDLQIPPPNI
PRD
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| BDBM50102880 |
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| n/a |
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| Name | BDBM50102880 |
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| Synonyms: | 8,9,10-Trihydroxy-7-hydroxymethyl-6-oxa-1,3-diaza-spiro[4.5]decane-2,4-dione | CHEMBL97548 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H12N2O7 |
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| Mol. Mass. | 248.1901 |
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| SMILES | OCC1O[C@@]2(NC(=O)NC2=O)C(O)[C@@H](O)[C@@H]1O |
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| Structure | 
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