| Reaction Details |
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 | Report a problem with these data |
| Target | Vesicular glutamate transporter 3 |
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| Ligand | BDBM50113318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213568 (CHEMBL816125) |
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| Ki | 167000±n/a nM |
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| Citation |  Carrigan, CN; Bartlett, RD; Esslinger, CS; Cybulski, KA; Tongcharoensirikul, P; Bridges, RJ; Thompson, CM Synthesis and in vitro pharmacology of substituted quinoline-2,4-dicarboxylic acids as inhibitors of vesicular glutamate transport. J Med Chem45:2260-76 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vesicular glutamate transporter 3 |
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| Name: | Vesicular glutamate transporter 3 |
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| Synonyms: | Slc17a8 | VGLU3_RAT | Vglut3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64750.88 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_213568 |
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| Residue: | 588 |
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| Sequence: | MPFNAFDTFKEKILKPGKEGVKNAVGDSLGILQRKLDGTNEEGDAIELSEEGRPVQTSRA
RAPVCDCSCCGIPKRYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTA
QFNWDPETVGLIHGSFFWGYIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARV
HYGCVMCVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGV
LVQYIGWASVFYIYGMFGIIWYMFWLLQAYECPAVHPTISNEERTYIETSIGEGANLASL
SKFNTPWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPH
MVMTIVVPIGGQLADYLRSRKILTTTAVRKIMNCGGFGMEATLLLVVGFSHTKGVAISFL
VLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEW
QNVFLIAALVHYSGVIFYGVFASGEKQDWADPENLSEEKCGIIDQDELAEETELNHEAFV
SPRKKMSYGATTQNCEVQKTDRRQQRESAFEGEEPLSYQNEEDFSETS
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| BDBM50113318 |
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| n/a |
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| Name | BDBM50113318 |
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| Synonyms: | 6-Styryl-quinoline-2,4-dicarboxylic acid | CHEMBL76124 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H13NO4 |
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| Mol. Mass. | 319.3108 |
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| SMILES | OC(=O)c1cc(C(O)=O)c2cc(\C=C\c3ccccc3)ccc2n1 |
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| Structure | 
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