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TargetCorticotropin-releasing factor receptor 2
LigandBDBM50119607
Substrate/Competitorn/a
Meas. Tech.ChEMBL_51278 (CHEMBL664980)
IC50 6.2±n/a nM
Citation Rivier, J; Gulyas, J; Kirby, D; Low, W; Perrin, MH; Kunitake, K; DiGruccio, M; Vaughan, J; Reubi, JC; Waser, B; Koerber, SC; Martinez, V; Wang, L; Taché, Y; Vale, W Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists. J Med Chem45:4737-47 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Corticotropin-releasing factor receptor 2
Name:Corticotropin-releasing factor receptor 2
Synonyms:CRF-R 2 | CRF2 | CRF2R | CRFR2_HUMAN | CRH-R 2 | CRH2R | CRHR2 | Corticotropin releasing factor receptor 2 | Corticotropin-releasing factor receptor 2 (CRF-2) | Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | Corticotropin-releasing hormone receptor 2
Type:Enzyme
Mol. Mass.:47694.70
Organism:Homo sapiens (Human)
Description:Q13324
Residue:411
Sequence:
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALV
ERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVN
YLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESN
EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIV
AWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYC
FFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
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  Blast E-value cutoff:
BDBM50119607
n/a
NameBDBM50119607
Synonyms:CHEMBL440057 | E G P P I S I D L S L E L L R K M I E I E K Q E K E K Q Q A A N N R L L L D T I I-NH2(r/h CRF) | Human corticotropin releasing factor
TypeSmall organic molecule
Emp. Form.C208H343N59O64S2
Mol. Mass.4758.436
SMILESn/a
Structure
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